Helping patients with chronic pain is one of the greatest and most common challenges the rheumatologists face. Many strides have been made in pain management in recent years, and this issue of the Rheumatic Disease Clinics of North America provides the most up-to-date information essential to today's clinical practice. Topics covered include pain mechanisms, placebo response, epidemiology of musculoskeletal pain, pain measurement in the clinical setting, pharmacotherapy including opioids and topical agents, dietary considerations, antidepressants, complementary treatments, psychological interventions, and lifestyle modifications.

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