Bitter Pills started as a magazine story, inspired by Stephen Fried's wife's frightening reaction to an antibiotic. After he won a National Magazine Award for that article, he expanded his investigation into this book. What he has uncovered is astounding, starting with the fact that, in the U.S. alone, between 45,000 and 200,000 people die annually of reactions to legal drugs (2 to 9 percent of the 2.3 million Americans who die each year) versus the 5,000 to 10,000 who die of illegal drug use. As Fried compulsively investigates what happened to his wife and how reactions like hers were considered statistically insignificant by drug companies and the FDA, he learns things most of us don't want to know about the mechanisms that cause pills to land on pharmacy shelves. Chances are, after reading Bitter Pills , you'll be much more careful about accepting prescriptions for new medications.

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