Oral squamous cell carcinoma is a fatality that conjures images of the worse kinds in the minds of the sufferer and those related. The therapeutic modalities employed are insufficient in treating the disease. Therefore, the understanding of the role of host immunity in treatment protocols is important. This research work is an attempt towards understanding the pathobiology of tumor invasiveness and the role of host immunity in defense against the metastatic carcinomatous cells in regional lymph nodes.

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