Sylvia Tait (nee Wardropper) was trained as a zoologist and James Tait as a physicist, although they have both become well known endocrinologists. They first collaborated in the discovery of aldosterone (a salt retaining hormone) and then (mainly with the Nobel Prize Winner, Professor T Reichstein) isolated and identified it. They married in 1956 and were elected together to the Fellowship of the Royal Society in 1959. Aldosterone was found to cause hypertension and heart disease in a significant number of patients. These can often be successfully treated by surgery (if due to an adrenal tumour) or by anti-aldosterone compounds. These events are described in this book with personal histories. The authors were in contact with scientists involved in three other discoveries. These were the DNA double helix, oral chemical contraceptives and saturation analysis (or immunoassay). These are described with the emphasis on the interactions of scientists such as R Gosling, M Wilkins and R...

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