High Quality Content by WIKIPEDIA articles! DecisionDx-UM is a prognostic test that accurately determines the metastatic risk associated with ocular melanoma tumors of the eye. Ocular melanoma is a term commonly used to describe tumors of the uveal tract such as uveal melanoma, choroidal melanoma, ciliary body melanoma, and iris melanoma. The DecisionDx-UM test was clinically validated on these tumors of the uveal tract. DecisionDx-UM assesses the gene expression profile (GEP) of a subset of genes which are differentially expressed in primary tumor cells compared to cells that have undergone transformation to a metastatic phenotype. The test classifies tumors as Class 1A (low metastatic risk), Class 1B (long-term metastatic risk), or Class 2 (immediate, high metastatic risk). Also referred to as the gene expression profile, the test has been directly compared to all other clinical and pathologic factors, such as chromosome 3 status (monosomy 3), cytopathology and tumor size and the...

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