High Quality Content by WIKIPEDIA articles! The artificial sweetener aspartame has been the subject of several controversies since its initial approval by the U.S. Food and Drug Administration (FDA) in 1974. The FDA approval of aspartame was highly contested, with critics alleging that the quality of the initial research supporting its safety was inadequate and flawed and that conflicts of interest marred the approval of aspartame. In 1987, the U.S. Government Accountability Office concluded that the food additive approval process had been followed properly for aspartame. In spite of this, critics such as activist Betty Martini have promoted claims, undocumented in the medical literature, that numerous health risks (such as multiple sclerosis, systemic lupus, methanol toxicity, blindness, spasms, shooting pains, seizures, headaches, depression, anxiety, memory loss, birth defects and death) are associated with the consumption of aspartame in normal doses. These health risk claims have...

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