High Quality Content by WIKIPEDIA articles! The underlying mechanisms of schizophrenia, a mental disorder characterized by a disintegration of the processes of thinking and of emotional responsiveness, are complex. A number of theories attempt to explain the link between altered brain function and schizophrenia. One of the most important is the dopamine hypothesis. This attributes psychosis to the faulty distribution, regulation, and function of dopaminergic neurons. Specifically, atypicallity is observed within the D2 subtype, a common target for all antipsychotic drugs. Along with glutamate, dopamine is involved in the advancement and reinforcement of the abnormal thought patterns in schizophrenia. Similarly, dopamine facilitates abnormal long term potentiation within the striatum, basal ganglia, cingulate cortex (specifically the cingulate gyrus), and prefrontal cortex, among other limbic system structures. Данное издание представляет собой компиляцию сведений, находящихся в...

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