Asymmetric hydrogenation
Автор:
Jesse Russell,Ronald Cohn, 105 стр., издатель:
"Книга по Требованию", ISBN:
978-5-5092-9558-4
High Quality Content by WIKIPEDIA articles! Asymmetric hydrogenation is a chemical reaction that adds two atoms of hydrogen to a target (substrate) molecule with three dimensional spatial selectivity. Critically, this selectivity does not come from the target molecule itself but from other reagents or catalysts present in the reaction. This allows spatial information (what chemists may refer to as chirality) to transfer from one molecule to the target, forming the product as a single enantiomer. The chiral information is most commonly contained in a catalyst and, in this case, the information in a single molecule of catalyst may be transferred to many substrate molecules, effectively amplifying the amount of chiral information present. Many similar processes occur in nature, where a single chiral molecule like an enzyme can produce many other chiral molecules, like glucose or amino acids, that a cell needs to function. By imitating this process, chemists can generate many novel...