Mir-92 microRNA precursor family
Автор:
Jesse Russell,Ronald Cohn, 100 стр., издатель:
"Книга по Требованию", ISBN:
978-5-5088-0044-4
High Quality Content by WIKIPEDIA articles! The miR-92 microRNAs are short single stranded non-protein coding RNA fragments initially discovered incorporated into an RNP complex with a proposed role of processing RNA molecules and further RNP assembly. Mir-92 has been mapped to the human genome as part of a larger cluster at chromosome 13q31.3, where it is 22 nucleotides in length but exists in the genome as part of a longer precursor sequence. There is an exact replica of the mir-92 precursor on the X chromosome.MicroRNAs are endogenous triggers of the RNAi pathway which involves several ribonucleic proteins (RNPs) dedicated to repressing mRNA molecules via translation inhibition and/or induction of mRNA cleavage. miRNAs are themselves matured from their long RNA precursors by ribonucleic proteins as part of a 2 step biogenesis mechanism involving RNA polymerase 2. Данное издание представляет собой компиляцию сведений, находящихся в свободном доступе в среде Интернет в целом, и в...