Gamma-butyrobetaine dioxygenase
Автор:
Jesse Russell,Ronald Cohn, 101 стр., издатель:
"Книга по Требованию", ISBN:
978-5-5086-1428-7
High Quality Content by WIKIPEDIA articles! Gamma-butyrobetaine dioxygenase (also known as BBOX, GBBH or ?-butyrobetaine hydroxylase) is an enzyme that in humans is encoded by the BBOX1 gene. Gamma-butyrobetaine dioxygenase catalyses the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthesis pathway.Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation. In humans, gamma-butyrobetaine dioxygenase expression can be found in kidney (high), liver (moderate), and brain (very low).BBOX1 has recently been identified as a potential cancer gene on the basis of a large-scale microarray data analysis. Данное издание представляет собой компиляцию сведений, находящихся в свободном доступе в среде Интернет в целом, и в информационном сетевом ресурсе "Википедия" в частности. Собранная по частотным запросам указанной тематики, данная компиляция построена по принципу подбора...