High Quality Content by WIKIPEDIA articles! The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6 gene. It is a member of the organic anion transporter (OAT) family of proteins. OAT1 is a transmembrane protein that is expressed in the brain, the placenta, the eyes, smooth muscles, and the basolateral membrane of proximal tubular cells of the kidneys. It plays a central role in renal organic anion transport. Along with OAT3, OAT1 mediates the uptake of a wide range of relatively small and hydrophilic organic anions from plasma into the cytoplasm of the proximal tubular cells of the kidneys. From there, these substrates are transported into the lumen of the nephrons of the kidneys for excretion. OAT1 homologs have been identified in rats, mice, rabbits, pigs, flounders, and nematodes. Данное издание представляет собой компиляцию сведений, находящихся в свободном доступе в среде Интернет в...

В наличии:
	Books.Ru - 1128 руб.	Перейти
Под заказ:
	OZON.ru - 1125 руб.	Перейти

Рейтинг книги: 5 из 5, 8 голос(-ов).