High Quality Content by WIKIPEDIA articles! Protein function prediction methods are used to assign biological or biochemical roles to proteins that are poorly studied or predicted proteins based on genomic sequence data. These predictions are often driven by data-intensive computational procedures. Sources of information may come from nucleic acid sequence homology, gene expression profiles, protein domain structures, text mining of publications, phylogenetic profiles, phenotypic profiles, and protein-protein interaction. It should be noted that protein function is a broad term: the roles of proteins range from catalysis of biochemical reactions to transport to signal transduction, and a single protein may play a role in multiple processes or cellular pathways. Generally, function can be thought of as, "anything that happens to or through a protein". The Gene Ontology Consortium provides a useful classification of functions, based on a dictionary of well-defined terms divided into...

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