Germinal center B-cell like diffuse large B-cell lymphoma
Автор:
Jesse Russell,Ronald Cohn, 101 стр., издатель:
"Книга по Требованию", ISBN:
978-5-5082-1233-9
High Quality Content by WIKIPEDIA articles! Gene expression profiling has revealed that Diffuse Large B-Cell Lymphoma (DLBCL) is composed of at least 3 different sub-groups, each having distinct oncogenic mechanisms that respond differently to therapies. Germinal Center B-Cell like (GCB) DLBCLs appear to arise from normal germinal center B cells, while Activated B-cell like (ABC) DLBCLs are thought to arise from postgerminal center B cells that are arrested during plasmacytic differentiation. The differences in gene expression between GCB DLBCL and ABC DLBCL, are as vast as the differences between distinct types of leukemia, but these conditions have historically been grouped together and treated as the same disease. Данное издание представляет собой компиляцию сведений, находящихся в свободном доступе в среде Интернет в целом, и в информационном сетевом ресурсе "Википедия" в частности. Собранная по частотным запросам указанной тематики, данная компиляция построена по принципу подбора...