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Alzheimer

Alzheimer's disease biomarkers

Автор: Jesse Russell,Ronald Cohn, 115 стр., издатель: "Книга по Требованию", ISBN: 978-5-5142-7579-3

High Quality Content by WIKIPEDIA articles! The Alzheimer's disease biomarkers are neurochemical indicators used to assess the risk or presence of the disease. The biomarkers can be used to diagnose Alzheimer's disease (AD) in a very early stage, but they also provide objective and reliable measures of disease progress. It is imperative to diagnose AD disease as soon as possible, because neurophathologic changes of AD precede the symptoms by years. It is well known how beta amyloid (A?) is a good indicator of AD disease, which has facilitated doctors to accurately pre-diagnose cases of AD disease. When A? peptide is released by proteolytic cleavage of amyloid precursor protein, some A? peptides that are solubilized are detected in CSF and blood plasma which makes AB peptides a promising candidate for biological markers. It has been shown that the beta-amyloid biomarker shows 80% or above sensitivity and specificity, in distinguishing AD from dementia. It is believed that beta-amyloid...
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