Nitroaldol reaction
Автор:
Jesse Russell,Ronald Cohn, 100 стр., издатель:
"Книга по Требованию", ISBN:
978-5-5138-5302-2
High Quality Content by WIKIPEDIA articles! The Henry Reaction (also referred to as the nitro-aldol reaction) is a classic carbon–carbon bond formation reaction in organic chemistry. Discovered in 1895 by L. Henry, it is the combination of a nitroalkane and an aldehyde or ketone in the presence of a base to form ?-Nitro alcohols. This type of reaction is commonly referred to as a "nitro-aldol" reaction (nitroalkane, aldehyde, and alcohol) It is nearly analogous to the aldol reaction that had been discovered 23 years prior that couples two carbonyl compounds to form ?-hydroxy carbonyl compounds known as "aldols" (aldehyde and alcohol). The Henry reaction is a useful technique in the area organic chemistry due to the synthetic utility of its corresponding products, as they can be easily converted to other useful synthetic intermediates. These conversions include subsequent dehydration to yield nitroalkenes, oxidation of the secondary alcohol to yield ?-nitro ketones, or reduction of the...