At the heart of organic chemistry is the effective synthesis of natural products or compounds, which are important for pharmaceuticals and agrochemicals, for example. These syntheses often include new reactions and novel concepts in organic chemistry, such that there is always a need for innovative strategies and improved methods. This textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of total synthesis with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, whatever the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as...

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