Mechanisms in Transcriptional Regulation provides a concise discussion of the fundamental concepts in transcription and its regulation. Beginning with an overview of RNA polymerases and the general transcriptional machinery, this book goes on to cover the mechanisms of transcriptional activation, the histone code hypothesis, the epigenetic control of transcription, and combinatorial control in signaling and development. Mechanisms in Transcriptional Regulation contains many features designed to aid understanding. More than 80 figures crystallize and amplify the ideas presented in the text. Boxes set off from the main text offer background information on important theoretical concepts and experimental methods. Thought–provoking problems test students’ understanding of key concepts. Extensive reading lists included in each chapter provide guidance for further studies. In addition, the book is accompanied by a website that includes all the art from the book in...

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