S ynthesis is one of the major endeavours of the organic chemist, and the design of a successful synthesis requires a sound knowledge of functional group chemistry, stereochemistry and organic reaction mechanisms. Organic Synthetic Methods introduces the major methods of creating carbon–carbon and carbon–nitrogen bonds, along with functional group interconversions (Oxidation, reduction, halogenation). The use of protecting groups and solid–phase methods are also discussed. The analysis of the structure of a target molecule, in terms of the structural consequences of synthetic reactions, is introduced to enable the student to identify key dissections and building blocks and hence develop a suitable synthetic method. Examples of the synthesis of labelled compounds are also provided.

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